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Veterinary Tips & Articles

Displaying posts in Veterinary Specialist Articles

A Review of Canine and Feline Oral Tumors

By Dr. Daniel T. Carmichael, DVM, Diplomate AVDC

Posted in Dentistry, Veterinary Specialist Articles

The oral cavity is a common site of malignant neoplasia in both the dog and the cat. Tumors of the oral cavity can be classified as odontogenic tumors (neoplasia arising from tooth-forming tissues), non-odontogenic tumors, or non-neoplastic lesions. In dogs, the non-odontogenic tumors include the three most common malignant oral neoplasms: melanoma, squamous cell carcinoma, and fibrosarcoma. Odontogenic tumors, generally considered to be rare, are actually common if the odontogenic benign...

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The Melanoma Vaccine

By Dr. Edwin Brodsky, DVM, Diplomate ACVIM (Oncology)

Posted in Oncology, Veterinary Specialist Articles

Oral melanoma is the most common malignant oral tumor in dogs. Oral melanomas are both locally aggressive and systemically aggressive (up to 80% metastatic rate). Initial work-up for oral melanomas should include a minimal data base (CBC, chemistry, and urinalysis), lymph node evaluation with cytology or biopsy, three-view chest radiographs and biopsy confirmation of the oral melanoma.

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Targeted Therapy

By Dr. Edwin Brodsky, DVM, Diplomate ACVIM (Oncology)

Posted in Oncology, Veterinary Specialist Articles

Recently, a great deal of research has been done in both normal and cancerous cells regarding the signals involved in cell growth, differentiation and survival.  Normal cells receive signals from outside the cell via molecules called growth factors. These growth factors bind to growth factor receptors on the cell membrane. The receptors become activated and start a downstream signaling cascade inside the cell which eventually reaches the nucleus where the signal exerts its influence on the c...

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Mast Cell Tumor Proliferation

By Dr. Edwin Brodsky, DVM, Diplomate ACVIM (Oncology)

Posted in Oncology, Veterinary Specialist Articles

Mast cell tumors are the most common cutaneous malignancy in dogs. One of the most important prognostic factors when treating mast cell tumors is the histologic grade. The histologic grade is a measure of how aggressive a tumor appears on a biopsy. Mast cell tumors are commonly graded using a three tier grading system.  Grade I mast cell tumors are well-differentiated, grade II mast cell tumors are moderately differentiated and grade III tumors are poorly differentiated. Post operative survi...

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Metronomic Chemotherapy

By Dr. Edwin Brodsky, DVM, Diplomate ACVIM (Oncology)

Posted in Oncology, Veterinary Specialist Articles

Dogs frequently present with masses along the eyelid margin. Benign canine eyelid masses outnumber malignant ones at a ratio of 3 to 1. Most of these masses are tumors of the meibomian glands that line the eyelid margins and normally supply lipids (meibum) to the tear film. As dogs age and develop numerous sebaceous skin tumors, they are also more likely to develop these minimally invasive meibomian tumors.

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Interventional Radiology Techniques

By Dr. Sean Hillock, Diplomate ACVIM

Posted in Internal Medicine, Radiology, Veterinary Specialist Articles

Since there is not an abundance of information about these procedures in the literature, the following general information will help you decide which patients may be possible candidates and allow you to adequately prepare owners prior to referral.

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Feline Dental Problems

By Dr. Daniel T. Carmichael, DVM, Diplomate AVDC

Posted in Ophthalmology, Veterinary Specialist Articles

There are a number of antibiotics that are available to treat corneal ulceration.  The appropriate antibiotic will specifically kill the opportunistic or contaminating bacteria within the corneal ulcer.  At our present level of laboratory science, it normally takes a few days before a veterinarian receives the results of bacterial culture and sensitivity tests.  Typically the results will indicate an antibiotic’s minimal inhibitory concentration (MIC) within the bloodstream to effectively tr...

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Chemotherapy in Veterinary Medicine

By Dr. Edwin Brodsky, DVM, Diplomate ACVIM (Oncology)

Posted in Oncology, Veterinary Specialist Articles

When people think of chemotherapy they generally assume horrible side effects such as severe vomiting, diarrhea, weight loss, lethargy and an overall poor quality of life.  However, in veterinary medicine, the majority of patients (80-85%) have minimal to no side effects when receiving chemotherapy. There are a couple of reasons for this result. First, in veterinary medicine, we do not use the large doses and aggressive chemotherapy protocols used in human medicine.  Our primary goal in vete...

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